Evaluation of the pharmacokinetics, dosimetry, and therapeutic efficacy for the α-particle-emitting transarterial radioembolization (αTARE) agent [225Ac]Ac-DOTA-TDA-Lipiodol® against hepatic tumors

Abstract Background The liver is a common site for metastatic disease for a variety of cancers, including colorectal cancer. Both primary and secondary liver tumors are supplied through the hepatic artery while the healthy liver is supplied by the portal vein. Transarterial radioembolization (TARE)...

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Prif Awduron:	Anders Josefsson, Angel G. Cortez, Harikrishnan Rajkumar, Joseph D. Latoche, Ambika P. Jaswal, Kathryn E. Day, Mohammadreza Zarisfi, Lora H. Rigatti, Ziyu Huang, Jessie R. Nedrow
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	SpringerOpen 2023-08-01
Cyfres:	EJNMMI Radiopharmacy and Chemistry
Pynciau:	Hepatocellular carcinoma Lipiodol® Targeted alpha therapy (TAT) Alpha-particle Dosimetry Actinium-225
Mynediad Ar-lein:	https://doi.org/10.1186/s41181-023-00205-3
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