Evaluation of the pharmacokinetics, dosimetry, and therapeutic efficacy for the α-particle-emitting transarterial radioembolization (αTARE) agent [225Ac]Ac-DOTA-TDA-Lipiodol® against hepatic tumors

Abstract Background The liver is a common site for metastatic disease for a variety of cancers, including colorectal cancer. Both primary and secondary liver tumors are supplied through the hepatic artery while the healthy liver is supplied by the portal vein. Transarterial radioembolization (TARE)...

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Asıl Yazarlar:	Anders Josefsson, Angel G. Cortez, Harikrishnan Rajkumar, Joseph D. Latoche, Ambika P. Jaswal, Kathryn E. Day, Mohammadreza Zarisfi, Lora H. Rigatti, Ziyu Huang, Jessie R. Nedrow
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	SpringerOpen 2023-08-01
Seri Bilgileri:	EJNMMI Radiopharmacy and Chemistry
Konular:	Hepatocellular carcinoma Lipiodol® Targeted alpha therapy (TAT) Alpha-particle Dosimetry Actinium-225
Online Erişim:	https://doi.org/10.1186/s41181-023-00205-3
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