Metabolic reprogramming during ineffective erythropoiesis in β-thalassemia/HbE disease

Ineffective erythropoiesis, the main cause of anemia in β-thalassemia disease, is characterized by dramatic expansion of erythroblasts and increased erythroblast cell death. The absence or reduction of β-globin chains causes an accumulation of excess α-globin chains and generates cytotoxic reactive...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Chanyanat Sukhuma, Donny Nauphar, Khanita Nuamsee, Wasinee Kheansaard, Kittiphong Paiboonsukwong, Alisa Wilantho, Chumpol Ngamphiw, Pornthip Chaichompoo, Sissades Tongsima, Saovaros Svasti, Phatchariya Phannasil
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2025-09-01
Цуврал:	Experimental and Molecular Pathology
Нөхцлүүд:	Metabolic reprogramming Metabolic genes Metabolism Ineffective erythropoiesis Β-Thalassemia/HbE disease
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0014480025000309
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!