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An atlas of genetic effects on the monocyte methylome across European and African populations

Abstract Background Genetic regulation of DNA methylation in immune cells may mediate complex disease risk. However, current epigenomic studies are constrained by microarray CpG coverage, mixed-cell tissues, and limited representation of diverse ancestries. Thus, we generated a whole-genome, multi-a...

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Huvudupphov: Wanheng Zhang, Chuan Qiu, Xiao Zhang, Zichen Zhang, Kuan-Jui Su, Zhe Luo, Minghui Liu, Bingxin Zhao, Lang Wu, Qing Tian, Hui Shen, Chong Wu, Hong-Wen Deng
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2026-03-01
Serie:Genome Medicine
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Länkar:https://doi.org/10.1186/s13073-026-01629-7
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