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Distinct functions for the Drosophila piRNA pathway in genome maintenance and telomere protection.

Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway has additional functions during development. Here...

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Autors principals: Jaspreet S Khurana, Jia Xu, Zhiping Weng, William E Theurkauf
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2010-12-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC3003142?pdf=render
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