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Distinct functions for the Drosophila piRNA pathway in genome maintenance and telomere protection.

Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway has additional functions during development. Here...

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Principais autores: Jaspreet S Khurana, Jia Xu, Zhiping Weng, William E Theurkauf
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Genetics
Acceso en liña:http://europepmc.org/articles/PMC3003142?pdf=render
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