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Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness

The diacylglycerol kinases (DGKs) are a family of enzymes responsible for the conversion of diacylglycerol (DAG) to phosphatidic acid (PA). In addition to their primary function in lipid metabolism, DGKs have recently been identified as potential therapeutic targets in multiple cancers, including gl...

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Gardado en:
Principais autores: Laryssa C. Manigat, Mitchell E. Granade, Suchet Taori, Charlotte Anne Miller, Luke R. Vass, Xiao-Ping Zhong, Thurl E. Harris, Benjamin W. Purow
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Assuntos:
DGKα
diacylglycerol kinase
macrophage
immune regulation
BMDM
wound healing
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2021.722469/full
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