Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness

The diacylglycerol kinases (DGKs) are a family of enzymes responsible for the conversion of diacylglycerol (DAG) to phosphatidic acid (PA). In addition to their primary function in lipid metabolism, DGKs have recently been identified as potential therapeutic targets in multiple cancers, including gl...

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Principais autores:	Laryssa C. Manigat, Mitchell E. Granade, Suchet Taori, Charlotte Anne Miller, Luke R. Vass, Xiao-Ping Zhong, Thurl E. Harris, Benjamin W. Purow
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-11-01
Serija:	Frontiers in Immunology
Teme:	DGKα diacylglycerol kinase macrophage immune regulation BMDM wound healing
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.722469/full
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