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Application of green analytical principles in the HPLC analysis of prednisolone derivatives: Method optimization and validation for nasal powder formulations

Glucocorticoids are a group of drugs increasingly used in modern medical practice due to their pronounced anti--inflammatory and immunosuppressive properties. In this study, prednisolone disodium phosphate and prednisolone acetate were analysed, with the aim of developing and validating an HPLC meth...

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Main Authors: Klarić Daniela Amidžić, Kovačić Jelena, Klarić Ilija, Bajt Petra, Pribolšan Lana, Križanić Erika, Nodilo Laura Nižić, Mornar Ana
Format: Artigo
Language:Inglês
Published: Sciendo 2025-12-01
Series:Acta Pharmaceutica
Subjects:
prednisolone disodium phosphate
prednisolone acetate
hplc-dad
validation
green analytical chemistry
Online Access:https://doi.org/10.2478/acph-2025-0032
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