Ligand dependent gene regulation by transient ERα clustered enhancers.
Unliganded Estrogen receptor alpha (ERα) has been implicated in ligand-dependent gene regulation. Upon ligand exposure, ERα binds to several EREs relatively proximal to the pre-marked, unliganded ERα-bound sites and affects transient but robust gene expression. However, the underlying mechanisms are...
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| Principais autores: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2020-01-01
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| Serier: | PLoS Genetics |
| Online adgang: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008516&type=printable |
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