LDH and PDH Activities in the Ischemic Brain and the Effect of Reperfusion—An Ex Vivo MR Study in Rat Brain Slices Using Hyperpolarized [1-¹³C]Pyruvate

Ischemic stroke is a leading cause for neurologic disability worldwide, for which reperfusion is the only available treatment. Neuroimaging in stroke guides treatment, and therefore determines the clinical outcome. However, there are currently no imaging biomarkers for the status of the ischemic bra...

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Auteurs principaux:	Gal Sapir, David Shaul, Naama Lev-Cohain, Jacob Sosna, Moshe J. Gomori, Rachel Katz-Brull
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2021-03-01
Collection:	Metabolites
Sujets:	ischemic stroke reperfusion lactate dehydrogenase pyruvate dehydrogenase dissolution dynamic nuclear polarization brain slices
Accès en ligne:	https://www.mdpi.com/2218-1989/11/4/210
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