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Benchmarking clustering algorithms on estimating the number of cell types from single-cell RNA-sequencing data

Abstract Background A key task in single-cell RNA-seq (scRNA-seq) data analysis is to accurately detect the number of cell types in the sample, which can be critical for downstream analyses such as cell type identification. Various scRNA-seq data clustering algorithms have been specifically designed...

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Autori principali: Lijia Yu, Yue Cao, Jean Y. H. Yang, Pengyi Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-02-01
Serie:Genome Biology
Accesso online:https://doi.org/10.1186/s13059-022-02622-0
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