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Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest

Senescent cells release a variety of cytokines, proteases, and growth factors collectively known as the senescence-associated secretory phenotype (SASP). Sustained SASP contributes to a pattern of chronic inflammation associated with aging and implicated in many age-related diseases. Here, we invest...

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Furkejuvvon:
Váldodahkkit: Martina Rossi, Carlos Anerillas, Maria Laura Idda, Rachel Munk, Chang Hoon Shin, Stefano Donega, Dimitrios Tsitsipatis, Allison B Herman, Jennifer L Martindale, Xiaoling Yang, Yulan Piao, Krystyna Mazan-Mamczarz, Jinshui Fan, Luigi Ferrucci, Peter F Johnson, Supriyo De, Kotb Abdelmohsen, Myriam Gorospe
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: eLife Sciences Publications Ltd 2023-04-01
Ráidu:eLife
Fáttát:
BAFF
SASP
senescence
paracrine
Liŋkkat:https://elifesciences.org/articles/84238
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