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Synthesis and HPLC-ECD Study of Cytostatic Condensed <i>O,N</i>-Heterocycles Obtained from 3-Aminoflavanones

Racemic chiral <i>O,N</i>-heterocycles containing 2-arylchroman or 2-aryl-2<i>H</i>-chromene subunit condensed with morpholine, thiazole, or pyrrole moieties at the C-3-C-4 bond were synthesized with various substitution patterns of the aryl group by the cyclization of <i>cis</i>- or <i>trans</i>-3-...

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Principais autores: Ádám Szappanos, Attila Mándi, Katalin Gulácsi, Erika Lisztes, Balázs István Tóth, Tamás Bíró, Anita Kónya-Ábrahám, Attila Kiss-Szikszai, Attila Bényei, Sándor Antus, Tibor Kurtán
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-10-01
Series:Biomolecules
Assuntos:
neber rearrangement
3-aminoflavanones
antiproliferative activity
TDDFT-ECD calculations
HPLC-ECD
3-(<i>N</i>-chloroacetylamino)-flavan-4-ol
Acceso en liña:https://www.mdpi.com/2218-273X/10/10/1462
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