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Induction of New Lactam Derivatives From the Endophytic Fungus Aplosporella javeedii Through an OSMAC Approach

Fermentation of the endophytic fungus Aplosporella javeedii on solid rice medium in presence of either 3.5% NaNO3 or 3.5% monosodium glutamate caused a significant change of the fungal metabolite pattern compared to fungal controls grown only on rice. Chemical investigation of the former fungal extr...

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Principais autores: Ying Gao, Fabian Stuhldreier, Laura Schmitt, Sebastian Wesselborg, Zhiyong Guo, Kun Zou, Attila Mándi, Tibor Kurtán, Zhen Liu, Peter Proksch
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-11-01
Serier:Frontiers in Microbiology
Fag:
Aplosporella javeedii
lactam derivatives
OSMAC approach
DFT-NMR
TDDFT-ECD
OR calculations
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2020.600983/full
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