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Effect of cytochrome P450 3A5 polymorphism on the pharmacokinetics of tacrolimus in renal transplant recipients

Background : Renal transplant is an effective treatment option for end-stage kidney disease and tacrolimus is one of the most commonly used immunosuppressant drugs in renal transplant patients. Tacrolimus is a substrate of cytochrome P450 3A5 (CYP3A5), and a narrow therapeutic index and large inter-...

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Principais autores: Yi Yi Htun, Nwe Nwe Than, Htar Kyi Swe
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society for Transplantation 2020-03-01
Series:Korean Journal of Transplantation
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Acceso en liña:http://journaleditor.inforang.com/journal/view.html?doi=10.4285/kjt.2020.34.1.24
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