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Digital quantitative tissue image analysis of hypoxia in resected pancreatic ductal adenocarcinomas

BackgroundTumor hypoxia is theorized to contribute to the aggressive biology of pancreatic ductal adenocarcinoma (PDAC). We previously reported that hypoxia correlated with rapid tumor growth and metastasis in patient-derived xenografts. Anticipating a prognostic relevance of hypoxia in patient tumo...

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Sábháilte in:
Príomhchruthaitheoirí: Iram Siddiqui, Jade Bilkey, Trevor D. McKee, Stefano Serra, Melania Pintilie, Trevor Do, Jing Xu, Ming-Sound Tsao, Steve Gallinger, Richard P. Hill, David W. Hedley, Neesha C. Dhani
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2022-08-01
Sraith:Frontiers in Oncology
Ábhair:
hypoxia
tumor microenvironment
ductal adenocarcinoma (PDAC)
tumor heterogeneity
image analysis
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fonc.2022.926497/full
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