p300: expanding beyond acetylation to mastermind lactylation-dependent tumorigenesis
The transcription coactivator p300 is canonically recognized as a histone acetyltransferase that orchestrates chromatin remodeling and gene expression. However, recent breakthroughs have expanded the catalytic landscape of p300 beyond acetylation to include lactylation, a metabolic stress induced mo...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2026-05-01
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| Serie: | Frontiers in Cell and Developmental Biology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fcell.2026.1811421/full |
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