Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus

<p>Abstract</p> <p>Background</p> <p>Human respiratory syncytial virus (RSV) is an important cause of lower respiratory tract disease in the paediatic population, immunocompromised individuals and the elderly worldwide. However, despite global efforts over the past several decades there are no comme...

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Hauptverfasser:	Headlam Madeleine J, Preston Faith M, Lau Wei-Har, Straub Claire P, Gorman Jeffery J, Collins Peter L, Spann Kirsten M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2011-05-01
Schriftenreihe:	Virology Journal
Schlagworte:	RSV NS1 attenuation
Online-Zugang:	http://www.virologyj.com/content/8/1/252
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