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Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus

<p>Abstract</p> <p>Background</p> <p>Human respiratory syncytial virus (RSV) is an important cause of lower respiratory tract disease in the paediatic population, immunocompromised individuals and the elderly worldwide. However, despite global efforts over the past several decades there are no comme...

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Principais autores: Headlam Madeleine J, Preston Faith M, Lau Wei-Har, Straub Claire P, Gorman Jeffery J, Collins Peter L, Spann Kirsten M
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2011-05-01
Serier:Virology Journal
Fag:
RSV
NS1
attenuation
Online adgang:http://www.virologyj.com/content/8/1/252
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