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A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum.

Nonenveloped viruses undergo conformational changes that enable them to bind to, disrupt, and penetrate a biological membrane leading to successful infection. We assessed whether cytosolic factors play any role in the endoplasmic reticulum (ER) membrane penetration of the nonenveloped SV40. We find...

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Autori principali: Christopher Paul Walczak, Madhu Sudhan Ravindran, Takamasa Inoue, Billy Tsai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-03-01
Serie:PLoS Pathogens
Accesso online:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004007&type=printable
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