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Examining Topoisomers of a Snake-Venom-Derived Peptide for Improved Antimicrobial and Antitumoral Properties

Ctn[15-34], the C-terminal section of crotalicidin (Ctn), a cathelicidin from a South American pit viper, is an antimicrobial and antitumoral peptide with remarkably longer stability in human serum than the parent Ctn. In this work, a set of topoisomers of both Ctn and Ctn[15-34], including the retr...

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Principais autores: Adam Carrera-Aubesart, Sira Defaus, Clara Pérez-Peinado, Daniel Sandín, Marc Torrent, Maria Ángeles Jiménez, David Andreu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-08-01
Serier:Biomedicines
Fag:
antimicrobial peptides
snake venom
crotalicidin
Ctn[15-34]
enantio-, retro-, and retroenantio peptides
topoisomer peptides
Online adgang:https://www.mdpi.com/2227-9059/10/9/2110
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