Myotoxin-3 from the Pacific Rattlesnake <i>Crotalus oreganus oreganus</i> Venom Is a New Microtubule-Targeting Agent

Microtubule targeting agents (MTA) are anti-cancer molecules that bind tubulin and interfere with the microtubule functions, eventually leading to cell death. In the present study, we used an in vitro microtubule polymerization assay to screen several venom families for the presence of anti-microtub...

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Autors principals:	María Cecilia González García, Caroline Radix, Claude Villard, Gilles Breuzard, Pascal Mansuelle, Pascale Barbier, Philipp O. Tsvetkov, Harold De Pomyers, Didier Gigmes, François Devred, Hervé Kovacic, Kamel Mabrouk, José Luis
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-11-01
Col·lecció:	Molecules
Matèries:	anti-microtubule agent snake venom crotamine tubulin
Accés en línia:	https://www.mdpi.com/1420-3049/27/23/8241
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