Obesity reduced survival with 5-fluorouracil and did not protect against chemotherapy-induced cachexia or immune cell cytotoxicity in mice

Fluorouracil/5-flourouracil (5FU) is a first-line chemotherapy drug for many cancer types; however, its associated toxicities contribute to poor quality of life and reduced dose intensities negatively impacting patient prognosis. While obesity remains a critical risk factor for most cancers, our und...

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書誌詳細

主要な著者:	Brandon N. VanderVeen, Thomas D. Cardaci, Sierra J. McDonald, Sarah S. Madero, Christian A. Unger, Brooke M. Bullard, Reilly T. Enos, Kandy T. Velázquez, Jason L. Kubinak, Daping Fan, E. Angela Murphy
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis Group 2022-12-01
シリーズ:	Cancer Biology & Therapy
主題:	chemotherapy inflammation skeletal muscle adipose tissue liver toxicity
オンライン･アクセス:	http://dx.doi.org/10.1080/15384047.2022.2108306
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