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Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients

Objective. Trauma patients (TP) frequently develop an imbalanced immune response that often causes infectious postinjury complications. Monocytes show a diminished capability of both producing proinflammatory cytokines and antigen presentation after trauma. TLR2, TLR4, and TLR9 recognize pathogens a...

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Autores principales: David Heftrig, Ramona Sturm, Elsie Oppermann, Kerstin Kontradowitz, Katrin Jurida, Lukas Schimunek, Mathias Woschek, Ingo Marzi, Borna Relja
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2017-01-01
Colección:Mediators of Inflammation
Acceso en línea:http://dx.doi.org/10.1155/2017/2608349
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