Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis

Abstract Background Enolase 1 (ENO1) is a conserved glycolytic enzyme that regulates glycolysis metabolism. However, its role beyond glycolysis in the pathophysiology of multiple myeloma (MM) remains largely elusive. Herein, this study aimed to elucidate the function of ENO1 in MM, particularly its...

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Detalles Bibliográficos

Principais autores:	Xuejie Gao, Qilin Feng, Qikai Zhang, Yifei Zhang, Chaolu Hu, Li Zhang, Hui Zhang, Guanli Wang, Ke Hu, Mengmeng Ma, Zhuning Wang, Yujie Liu, Dong An, Hongfei Yi, Yu Peng, Xiaosong Wu, Gege Chen, Xinyan Jia, Haiyan Cai, Jumei Shi
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-01-01
Series:	Journal of Biomedical Science
Assuntos:	Multiple myeloma ENO1 Mitophagy YWHAZ Chemoresistance
Acceso en liña:	https://doi.org/10.1186/s12929-024-01101-x
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