Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis

Abstract Background Enolase 1 (ENO1) is a conserved glycolytic enzyme that regulates glycolysis metabolism. However, its role beyond glycolysis in the pathophysiology of multiple myeloma (MM) remains largely elusive. Herein, this study aimed to elucidate the function of ENO1 in MM, particularly its...

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主要な著者:	Xuejie Gao, Qilin Feng, Qikai Zhang, Yifei Zhang, Chaolu Hu, Li Zhang, Hui Zhang, Guanli Wang, Ke Hu, Mengmeng Ma, Zhuning Wang, Yujie Liu, Dong An, Hongfei Yi, Yu Peng, Xiaosong Wu, Gege Chen, Xinyan Jia, Haiyan Cai, Jumei Shi
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-01-01
シリーズ:	Journal of Biomedical Science
主題:	Multiple myeloma ENO1 Mitophagy YWHAZ Chemoresistance
オンライン･アクセス:	https://doi.org/10.1186/s12929-024-01101-x
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