A mathematical framework for estimating pathogen transmission fitness and inoculum size using data from a competitive mixtures animal model.
We present a method to measure the relative transmissibility ("transmission fitness") of one strain of a pathogen compared to another. The model is applied to data from "competitive mixtures" experiments in which animals are co-infected with a mixture of two strains. We observe the mixture in each a...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2011-04-01
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| coleção: | PLoS Computational Biology |
| Acesso em linha: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002026&type=printable |
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