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A mathematical framework for estimating pathogen transmission fitness and inoculum size using data from a competitive mixtures animal model.

We present a method to measure the relative transmissibility ("transmission fitness") of one strain of a pathogen compared to another. The model is applied to data from "competitive mixtures" experiments in which animals are co-infected with a mixture of two strains. We observe the mixture in each a...

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Detaylı Bibliyografya
Asıl Yazarlar: James M McCaw, Nimalan Arinaminpathy, Aeron C Hurt, Jodie McVernon, Angela R McLean
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2011-04-01
Seri Bilgileri:PLoS Computational Biology
Online Erişim:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002026&type=printable
Etiketler: Etiketle
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