Hypoxia-inducible factors: master regulators of hypoxic tumor immune escape
Abstract Hypoxia, a common feature of the tumor microenvironment in various types of cancers, weakens cytotoxic T cell function and causes recruitment of regulatory T cells, thereby reducing tumoral immunogenicity. Studies have demonstrated that hypoxia and hypoxia-inducible factors (HIFs) 1 and 2 a...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2022-06-01
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| coleção: | Journal of Hematology & Oncology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s13045-022-01292-6 |
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