क्यूआर कोड

Friedreich's ataxia (GAA)n•(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae.

Expansions of trinucleotide GAA•TTC tracts are associated with the human disease Friedreich's ataxia, and long GAA•TTC tracts elevate genome instability in yeast. We show that tracts of (GAA)(230)•(TTC)(230) stimulate mitotic crossovers in yeast about 10,000-fold relative to a "normal" DNA sequence;...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Wei Tang, Margaret Dominska, Patricia W Greenwell, Zachary Harvanek, Kirill S Lobachev, Hyun-Min Kim, Vidhya Narayanan, Sergei M Mirkin, Thomas D Petes
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science (PLoS) 2011-01-01
श्रृंखला:PLoS Genetics
ऑनलाइन पहुंच:http://europepmc.org/articles/PMC3020933?pdf=render
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