Photoimmunotherapy targeting biliary‐pancreatic cancer with humanized anti‐TROP2 antibody

Abstract Photoimmunotherapy (PIT) is a new type of tumor‐specific treatment utilizing monoclonal antibody (mAb)‐photosensitizer conjugates and near‐infrared (NIR) light irradiation. One potential PIT target, the type I transmembrane protein TROP2, is expressed at high levels in many cancers, includi...

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Hlavní autoři:	Takashi Nishimura, Makoto Mitsunaga, Ryoichi Sawada, Masayuki Saruta, Hisataka Kobayashi, Noriko Matsumoto, Toru Kanke, Hiroyuki Yanai, Koji Nakamura
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2019-12-01
Edice:	Cancer Medicine
Témata:	antibody‐drug conjugates molecular‐targeted therapy near‐infrared photoimmunotherapy TROP2
On-line přístup:	https://doi.org/10.1002/cam4.2658
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