PGAM5-Mediated PHB2 Dephosphorylation Contributes to Diabetic Cardiomyopathy by Disrupting Mitochondrial Quality Surveillance

Disruption of the mitochondrial quality surveillance (MQS) system contributes to mitochondrial dysfunction in diabetic cardiomyopathy (DCM). In this study, we observed that cardiac expression of phosphoglycerate mutase 5 (PGAM5), a mitochondrial Ser/Thr protein phosphatase, is upregulated in mice wi...

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Detalhes bibliográficos

Principais autores:	Rongjun Zou, Jun Tao, Jie He, Chaojie Wang, Songtao Tan, Yu Xia, Xing Chang, Ruibing Li, Ge Wang, Hao Zhou, Xiaoping Fan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Association for the Advancement of Science (AAAS) 2022-01-01
coleção:	Research
Acesso em linha:	https://spj.science.org/doi/10.34133/research.0001
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