Biochemical, Biophysical and Functional Characterization of an Insoluble Iron Containing Hepcidin–Ferritin Chimeric Monomer Assembled Together with Human Ferritin H/L Chains at Different Molar Ratios

Hepcidin and ferritin are key proteins of iron homeostasis in mammals. In this study, we characterize a chimera by fusing camel hepcidin to a human ferritin H-chain to verify if it retained the properties of the two proteins. The construct (HepcH) is expressed in <i>E. coli</i> in an insoluble and i...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Mohamed Boumaiza, Imene Fhoula, Fernando Carmona, Maura Poli, Michela Asperti, Alessandra Gianoncelli, Michela Bertuzzi, Paolo Arosio, Mohamed Nejib Marzouki
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2021-12-01
Цуврал:	Current Issues in Molecular Biology
Нөхцлүүд:	camel hepcidin human hepcidin ferroportin human ferritin H/L chains iron mass spectroscopy
Онлайн хандалт:	https://www.mdpi.com/1467-3045/44/1/9
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!