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Biochemical, Biophysical and Functional Characterization of an Insoluble Iron Containing Hepcidin–Ferritin Chimeric Monomer Assembled Together with Human Ferritin H/L Chains at Different Molar Ratios

Hepcidin and ferritin are key proteins of iron homeostasis in mammals. In this study, we characterize a chimera by fusing camel hepcidin to a human ferritin H-chain to verify if it retained the properties of the two proteins. The construct (HepcH) is expressed in <i>E. coli</i> in an insoluble and i...

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Bibliografiska uppgifter
Huvudupphov: Mohamed Boumaiza, Imene Fhoula, Fernando Carmona, Maura Poli, Michela Asperti, Alessandra Gianoncelli, Michela Bertuzzi, Paolo Arosio, Mohamed Nejib Marzouki
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2021-12-01
Serie:Current Issues in Molecular Biology
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Länkar:https://www.mdpi.com/1467-3045/44/1/9
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