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TCRpred: incorporating T-cell receptor repertoire for clinical outcome prediction

T-cell receptor (TCR) plays critical roles in recognizing antigen peptides and mediating adaptive immune response against disease. High-throughput technologies have enabled the sequencing of TCR repertoire at the single nucleotide level, allowing researchers to characterize TCR sequences with high r...

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Main Authors: Meiling Liu, Yang Liu, Li Hsu, Qianchuan He
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Genetics
Subjects:
CDR3
clinical outcome prediction
high dimensions
high throughput sequencing
T-cell receptor
TCR repertoire
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1345559/full
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