TCR β CDR3 repertoire remodeling in pediatric myocarditis reveals clonal expansion and disease-associated public clonotypes

BackgroundPediatric myocarditis is an inflammatory disease of the heart with heterogeneous clinical presentations and poorly understood immune mechanisms. T cell receptor (TCR) repertoire profiling provides insights into disease-associated adaptive immune responses.MethodsWe performed high-throughpu...

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Autori principali:	Xixiong Lin, Xing Zhang, Liping Zhang, Linhu Hui, Zhongjian Su, Xingzhu Liu, Bin Li, Jun Li, Yanfei Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-02-01
Serie:	Frontiers in Immunology
Soggetti:	antigen specificity CDR3 diversity clonal expansion pediatric myocarditis TCR repertoire
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1711681/full
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