Design and synthesis of fluorine aromatic scaffolds containing drugs approved by the US FDA from 2002 to 2022

There are totally 93 fluorine aromatic scaffolds containing drugs approved by U.S. Food and Drug Administration from 2002 to 2022. The proportion of drugs containing fluorinated aromatic skeleton in approved drugs is increasing in recent ten years, which indicates the unique and important attributes...

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Главные авторы:	Pengfei Xu, Lijun Zhu, Desheng Zhang, Zilong Li, Raoling Ge, Qiang Tian
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2024-01-01
Серии:	Results in Chemistry
Предметы:	Fluorine aromatic FDA-approved drugs Clinical application Chemical synthesis Medicinal chemistry
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2211715624001425
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