Synthetic strategies and therapeutic insights into FDA-approved indole-containing drugs

Indole is a privileged heteroaromatic scaffold in medicinal chemistry, characterised by its unique physicochemical properties, hydrogen-bonding potential, and bioisosteric versatility. Over the past decades, numerous indole-containing drugs have been approved by the Food and Drug Administration (FDA...

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Autors principals:	Tengjiao Yang, Yanfeng Zhang, Peng Liu, Peng Qi, Xiankai Li, Wubin Zhi, Lijie Zhao
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2026-12-01
Col·lecció:	Journal of Enzyme Inhibition and Medicinal Chemistry
Matèries:	Indole FDA-approved drugs synthesis clinical application
Accés en línia:	https://www.tandfonline.com/doi/10.1080/14756366.2026.2616556
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