Integrating Population Approaches With Physiologically Based Pharmacokinetic Models: A Novel Framework for Parameter Estimation
ABSTRACT Physiologically Based Pharmacokinetic (PBPK) modeling is a powerful tool in drug development that integrates drug‐specific information with physiological parameters to predict drug concentrations. However, parameter estimation in PBPK models presents significant challenges due to the large...
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| Huvudupphov: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Wiley
2026-01-01
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| Serie: | CPT: Pharmacometrics & Systems Pharmacology |
| Ämnen: | |
| Länkar: | https://doi.org/10.1002/psp4.70186 |
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