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Evolution of lineage-specific functions in ancient cis-regulatory modules

Morphological evolution is driven both by coding sequence variation and by changes in regulatory sequences. However, how cis-regulatory modules (CRMs) evolve to generate entirely novel expression domains is largely unknown. Here, we reconstruct the evolutionary history of a lens enhancer located wit...

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Bibliografiske detaljer
Principais autores: Stefan Pauls, Debbie K. Goode, Libero Petrone, Paola Oliveri, Greg Elgar
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2015-01-01
Serier:Open Biology
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Online adgang:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150079
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