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LINE-1 DNA Methylation, Smoking and Risk of Parkinson's Disease

Background: Long interspersed nucleotide element-1 (LINE-1) retrotransposons are located throughout the human genome. Those retaining an intact 5′ promoter can copy and insert themselves into the DNA of neural progenitor cells that express tyrosine hydroxylase, which may influence differentiation an...

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Váldodahkkit: Susan Searles Nielsen, Harvey Checkoway, Rondi A. Butler, Heather H. Nelson, Federico M. Farin, W.T. Longstreth Jr., Gary M. Franklin, Phillip D. Swanson, Karl T. Kelsey
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: SAGE Publishing 2012-11-01
Ráidu:Journal of Parkinson’s Disease
Liŋkkat:https://doi.org/10.3233/JPD-012129
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