LINE-1 DNA Methylation, Smoking and Risk of Parkinson's Disease

Background: Long interspersed nucleotide element-1 (LINE-1) retrotransposons are located throughout the human genome. Those retaining an intact 5′ promoter can copy and insert themselves into the DNA of neural progenitor cells that express tyrosine hydroxylase, which may influence differentiation an...

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Principais autores:	Susan Searles Nielsen, Harvey Checkoway, Rondi A. Butler, Heather H. Nelson, Federico M. Farin, W.T. Longstreth Jr., Gary M. Franklin, Phillip D. Swanson, Karl T. Kelsey
Format:	Artigo
Jezik:	Inglês
Izdano:	SAGE Publishing 2012-11-01
Serija:	Journal of Parkinson’s Disease
Online dostop:	https://doi.org/10.3233/JPD-012129
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