Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects

Background: Immunogenicity refers to the inherent ability of a molecule to stimulate an immune response. Aggregates are one of the major risk factors for the undesired immunogenicity of therapeutic antibodies (Ab) and may ultimately result in immune-mediated adverse effects. For Ab delivered by inha...

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מידע ביבליוגרפי

Principais autores:	Thomas Sécher, Elsa Bodier-Montagutelli, Christelle Parent, Laura Bouvart, Mélanie Cortes, Marion Ferreira, Ronan MacLoughlin, Guy Ilango, Otmar Schmid, Renaud Respaud, Nathalie Heuzé-Vourc’h
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2022-03-01
סדרה:	Pharmaceutics
נושאים:	therapeutic antibody aerosol aggregates immunogenicity
גישה מקוונת:	https://www.mdpi.com/1999-4923/14/3/671
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!