Decitabine Induces Change of Biological Traits in Myelodysplastic Syndromes via FOXO1 Activation

Decitabine (DAC) is considered to be a profound global DNA demethylation, which can induce the re-expression of silenced tumor suppressor genes. Little is known about the function of tumor suppressor gene FOXO1 in myelodysplastic syndromes (MDS). To address this issue, the study firstly investigated...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Zheng Zhang, Yan Jia, Feng Xv, Lu-xi Song, Lei Shi, Juan Guo, Chun-kang Chang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-01-01
Schriftenreihe:	Frontiers in Genetics
Schlagworte:	myelodysplastic syndromes DEGs FOXO1 PTEN TLR4
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fgene.2020.603956/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!