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Decitabine Induces Change of Biological Traits in Myelodysplastic Syndromes via FOXO1 Activation

Decitabine (DAC) is considered to be a profound global DNA demethylation, which can induce the re-expression of silenced tumor suppressor genes. Little is known about the function of tumor suppressor gene FOXO1 in myelodysplastic syndromes (MDS). To address this issue, the study firstly investigated...

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Bibliográfalaš dieđut
Váldodahkkit: Zheng Zhang, Yan Jia, Feng Xv, Lu-xi Song, Lei Shi, Juan Guo, Chun-kang Chang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2021-01-01
Ráidu:Frontiers in Genetics
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fgene.2020.603956/full
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