Diclofenac: A Nonsteroidal Anti-Inflammatory Drug Inducing Cancer Cell Death by Inhibiting Microtubule Polymerization and Autophagy Flux

Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammatory diseases induces cellular toxicity by increasing the production of reactive oxygen species (ROS) and impairing autophagic flux. In this study, we investigated whether diclofenac induces cancer cell death and the mec...

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Detalhes bibliográficos

Principais autores:	Soohee Choi, Suree Kim, Jiyoung Park, Seung Eun Lee, Chaewon Kim, Dongmin Kang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-05-01
coleção:	Antioxidants
Assuntos:	diclofenac autophagy microtubule depolymerization cell death combination cancer therapy
Acesso em linha:	https://www.mdpi.com/2076-3921/11/5/1009
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