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A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes

Trypanosomes have a trypanothione redox metabolism that provides the reducing equivalents for numerous essential processes, most being mediated by tryparedoxin (Tpx). While the biosynthesis and reduction of trypanothione are cytosolic, the molecular basis of the thiol redox homeostasis in the single...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Samantha Ebersoll, Marta Bogacz, Lina M Günter, Tobias P Dick, R Luise Krauth-Siegel
Hōputu: Artigo
Reo:Inglês
I whakaputaina: eLife Sciences Publications Ltd 2020-01-01
Rangatū:eLife
Ngā marau:
Urunga tuihono:https://elifesciences.org/articles/53227
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