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Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline–Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora

Previous studies have revealed the microbial metabolism of dietary choline in the gut, leading to its conversion into trimethylamine (TMA). Polymethoxyflavones (PMFs), exemplified by tangeretin, have shown efficacy in mitigating choline-induced cardiovascular inflammation. However, the specific mech...

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Bibliografische Detailangaben
Hauptverfasser: Yu Cao, Changlong Leng, Kuan Lin, Youwei Li, Meiling Zhou, Mei Zhou, Xiji Shu, Wei Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-03-01
Schriftenreihe:Molecules
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Online-Zugang:https://www.mdpi.com/1420-3049/29/6/1323
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