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Poly (ADP-Ribose) Polymerase Cleavage Monitored In Situ in Apoptotic Cells

During apoptosis, the activation of a family of cysteine proteases, or caspases, results in proteolytic cleavage of numerous substrates. Antibody probes specific for neoepitopes on protein fragments generated by caspase cleavage provide a means to monitor caspase activity at the level of the individ...

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Detalles Bibliográficos
Principais autores: Martha A. O'Brien, Richard A. Moravec, Terry L. Riss
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2001-04-01
Series:BioTechniques
Acceso en liña:https://www.future-science.com/doi/10.2144/01304pf01
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